It is therefore a "paragroup", as shown by the "*". In practice a paragroup might be one clade, "waiting" for its UEP to be discovered, or it might contain many clades.
There is some inconsistency and confusion concerning the correct use of the paragroup "star" (*). When reading journal articles and other sources care should be taken to ensure whether any or all possible sub-clades have been tested for and found to be negative. (A true paragroup should have been tested for all possible UEPs and found negative before it should have a star.)
Very many of the haplotypes identified as E-M35* in the literature have not been tested for M293. This is because this was not announced until Henn et al. (2008).
Putting these cases aside, the highest population of E-M35* by far appears to be in the Horn of Africa.