E-V65

From Haplowiki

E-V65 is a Y chromosome haplogroup defined by the mutation V65. It is a sub-clade of E-M78. It's phylogenetic name according to the E haplogroup page on ISOGG's website is E1b1b1a4.

This sub-clade is equivalent to the previously classified "beta cluster" discovered by Cruciani et al. (2004) and "characterized by the DYS413 23/21 pattern and the rare 10-repeat allele at DYS439". It is found in high levels in the Maghreb regions of far northern Africa. Cruciani et al. (2007) report levels of about 20% amongst Libyan Arab lineages, and about 30% amongst Morrocan Arabs.

It appears to be less common amongst Berbers, but still present in levels of >10%. The authors suggest a North African origin for this lineage. In Europe, only a few individuals were found in Italy and Greece.

Capelli et al. (2009) also studied the beta cluster in Europe (before the discovery of the V65 UEP). They found small amounts in Southern Italy, but also traces in Cantabria, Portugal and Galicia, with Cantabria having the highest level in Europe in their study, at 3.1% (out of 161 people).

STR Haplotypes

Cruciani database

Because of the European dominance of the E-M35 phylogeny project's database, meaning it has very little E-V65 data, it is useful to summarize the results from the Cruciani articles as follows...

E-V65	YCAIIa	YCAIIb	DYS413a	DYS413b	DYS19	DYS391	DYS393	DYS439	DYS460	DYS461	A10
modal	19	21	21	23	13	10	13	10	10	11	13
min	19	20	20	22	11	10	13	10	9	9	12
max	21	21	22	23	14	11	14	11	11	12	13
number	38	38	38	38	38	38	38	38	38	38	38

Here are all of the E-V65 haplotypes from Cruciani et al. (2007)...

'	HG	YCAIIa	YCAIIb	DYS413a	DYS413b	DYS19	DYS391	DYS393	DYS439	DYS460	DYS461	GATAA10	Absolute frequency
Central Italians	E-V65	21	19	23	21	13	10	13	10	10	11	13	1
Sicilians	E-V65	21	19	23	21	14	10	13	10	10	10	13	1
Sardinians	E-V65	20	19	23	21	13	10	13	10	10	10	13	1
Sardinians	E-V65	21	19	23	21	13	10	13	10	10	9	13	1
Sardinians	E-V65	21	19	23	21	13	10	13	10	10	10	13	2
Sardinians	E-V65	21	19	23	21	13	10	13	10	10	10	13	2
Continental Greeks	E-V65	21	19	23	21	13	10	13	10	10	11	13	1
Moroccans Arabs	E-V65	21	19	23	20	13	10	13	11	10	11	12	1
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	10	10	10	13	2
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	10	10	10	13	2
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	10	10	11	13	7
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	10	10	11	13	7
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	10	10	11	13	7
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	10	10	11	13	7
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	10	10	11	13	7
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	10	10	11	13	7
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	10	10	11	13	7
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	10	10	12	13	1
Moroccans Arabs	E-V65	21	19	23	21	11	10	13	11	10	11	13	1
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	11	10	11	13	3
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	11	10	11	13	3
Moroccans Arabs	E-V65	21	19	23	21	13	10	13	11	10	11	13	3
Moroccans Arabs	E-V65	21	19	23	21	13	11	13	10	10	11	13	1
Moyen Atlas Berbers	E-V65	21	19	23	21	13	10	13	10	10	10	13	1
Moyen Atlas Berbers	E-V65	21	19	23	21	13	10	13	10	10	11	13	3
Moyen Atlas Berbers	E-V65	21	19	23	21	13	10	13	10	10	11	13	3
Moyen Atlas Berbers	E-V65	21	19	23	21	13	10	13	10	10	11	13	3
Moyen Atlas Berbers	E-V65	21	19	23	21	13	10	13	10	11	11	13	1
Moyen Atlas Berbers	E-V65	21	21	23	21	13	10	13	10	9	11	13	2
Moyen Atlas Berbers	E-V65	21	21	23	21	13	10	13	10	9	11	13	2
Libyan Jews	E-V65	21	19	23	21	13	10	13	10	10	11	13	1
Libyan Arabs	E-V65	21	19	23	21	13	10	13	10	10	11	13	1
Libyan Arabs	E-V65	21	19	23	21	13	11	13	10	11	11	12	1
Egyptian Berbers	E-V65	21	19	22	21	13	10	13	11	10	10	13	1
Egyptian Berbers	E-V65	21	19	22	22	13	10	13	11	10	10	13	1
Egyptian Berbers	E-V65	21	19	23	21	13	10	14	10	10	11	13	2
Egyptian Berbers	E-V65	21	19	23	21	13	10	14	10	10	11	13	2
South Egypt	E-V65	21	19	23	21	13	10	13	10	10	11	13	1

YHRD database

Using YHRD and the above Cruciani information, combined with DYS389 values based on the E-M35 Project's only two E-V65 results, we can locate the following matches. This also requires excluding haplotypes with DYS392=16, which appear to belong to another haplogroup.

n	19	389i	389ii	390	391	392	393	385	438	439	437	448	456	458	635	ygatah4
(search parameters)	13	12	29	blank	10	11	13	blank	blank	10	blank	blank	blank	blank	blank	blank
15	13	12	29	23	10	11	13	17,18	10	10	NA	NA	NA	NA	NA	NA
5	13	12	29	23	10	11	13	17,18	10	10	14	NA	NA	NA	NA	NA
5	13	12	29	24	10	11	13	17,18	10	10	NA	NA	NA	NA	NA	NA
3	13	12	29	22	10	11	13	17,18	10	10	NA	NA	NA	NA	NA	NA
2	13	12	29	23	10	11	13	17,17	10	10	14	20	15	14	22	11
2	13	12	29	24	10	11	13	17,17	10	10	NA	NA	NA	NA	NA	NA
2	13	12	29	22	10	11	13	17,18	10	10	14	NA	NA	NA	NA	NA
2	13	12	29	24	10	11	13	18,18	10	10	14	20	15	14	22	10
2	13	12	29	24	10	11	13	18,19	10	10	NA	NA	NA	NA	NA	NA
1	13	12	29	22	10	11	13	17,18	10	10	14	21	15	14	21	11
1	13	12	29	22	10	11	13	16,17	10	10	14	20	15	14	21	11
1	13	12	29	22	10	11	13	17,18	10	10	14	20	15	15	21	11
1	13	12	29	23	10	11	13	17,19	10	10	NA	NA	NA	NA	NA	NA
1	13	12	29	24	10	11	13	16,18	10	10	NA	NA	NA	NA	NA	NA
1	13	12	29	22	10	11	13	18,18	10	10	14	20	15	14	21	11
1	13	12	29	24	10	11	13	17,17	10	10	14	NA	NA	NA	NA	NA
1	13	12	29	24	10	11	13	17,18	9	10	NA	NA	NA	NA	NA	NA
1*	13	12	29	23	10	11	13	14,14*	10	10	NA	NA	NA	NA	NA	NA
1	13	12	29	24	10	11	13	17,19	10	10	NA	NA	NA	NA	NA	NA
1	13	12	29	24	10	11	13	18,18	10	10	14	NA	NA	NA	NA	NA

A summary of where these matching haplotypes are found...

n of N	Geoposition [Population]	Metapopulation	Continent
19 of 132	Tunisia [Andalusian Arab]	Afroeurasian - Semitic	Africa
5 of 109	Belgium [Moroccan Berber]	Afroeurasian - Berber	Europe
3 of 155	Sfax, Tunisia [Tunisian]	Afroeurasian - Semitic	Africa
3 of 100	Northern Sardinia, Italy [Italian]	Eurasian - European	Europe
3 of 130	Rabat, Morocco [Arabs]	Afroeurasian - Semitic	Africa
2 of 54	Tunis, Tunisia [Tunisian]	Afroeurasian - Semitic	Africa
2 of 98	Rimini, Italy [Italian]	Eurasian - European - Western European	Europe
2 of 61	Marche, Italy [Tunisian]	Afroeurasian - Semitic	Europe
2 of 69	Rabat, Morocco [Berber]	Afroeurasian - Berber	Africa
2 of 566	Northern Portugal [Portuguese]	Eurasian - European - Western European	Europe
1 of 41	Blekinge, Sweden [Swedish]*	Eurasian - European - Western European	Europe
1 of 102	Ecuador [Mestizo]	Admixed	Latin America
1 of 34	Cundinamarca, Colombia [Mestizo]	Admixed	Latin America
1 of 97	Marche, Italy [Italian]	Eurasian - European - Western European	Europe
1 of 56	Sardinia, Italy [Sardinian]	Eurasian - European - Western European	Europe
1 of 533	Central Portugal [Portuguese]	Eurasian - European - Western European	Europe
1 of 111	Maracaibo, Venezuela [Mestizo]	Eurasian - European	Latin America
1 of 357	Mexico City, Mexico [Mestizo]	Admixed	Latin America
1 of 477	Stuttgart, Germany [German]	Eurasian - European - Western European	Europe
1 of 91	Caceres, Spain [Spanish]	Eurasian - European - Western European	Europe
1 of 52	Sohag, Upper Egypt [Egyptian]	Afroeurasian - Semitic	Africa

• The Swedish result has some other marker differences, such as DYS385 (see 14,14 above), and other close neighbours in Scandinavia, so it appears not to be a E-V65.