Timur et al. (2009)

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Timur et al. (2009)

Y-SNP haplogroups in the Antalya population in Turkish Republic

Rom J Leg Med 17 (1) 59 – 68 (2009) Romanian Society of Legal Medicine Received: 18.02.2009 / Accepted in revised form: 20.03.2009 http://www.rjlm.ro/doc/08-y-snphaplogroupsintheantalyapopulation.pdf

Contents 1 Authors 2 Abstract 3 Discussion on Internet 4 E-M35 results

Authors

Timur Serdar 1, Demircin Sema * 2

*) Corresponding author;

1) MD, Antalya Education and Research Hospital, Forensic Medicine Unit

2) Corresponding author: MD, Assoc. PhD, Aldeniz Üniversitesi, Tıp Fakültesi, Adli Tıp AD, Kampüs, 07070, Antalya, Turkey; E-Mail: sdemircin@akdeniz.edu.tr, Phone number : +90-242-2496376, Fax number: +90-242-2262877, Cell Phone : 0-505-7330828

Abstract

SNPs are known to be the most abundant source of sequence variation in the human genome. The SNPs in the NRY (non-recombining Y-chromosome) region which passes from father to son as unchanged haplotype-blocks escaping recombination, provides important advantages in the investigations of sexual assault crimes, in the cases of parentage testing especially if the mother or alleged father is unavailable for testing and in the evolutionary studies. The aim of this study, was to determine the frequencies of Y SNP markers and the haplogroups, in order to define the Y-chromosome SNP markers which are polymorphic, have high discrimination power and can be used in forensic investigations in the Antalya population. For each of 75 unrelated males from Antalya, 35 different Y-SNP markers were amplified in a single reaction using multiplex minisequencing method. In the study, 18 markers of them were found to be polymorphic. The most frequent YSNP markers with mutations were M139 (100%), SRY10831/SRY1532 (92%), M89 (85.3%), M213 (85.3%), M9 (44%), 92R7 (30.6%), 12F2 (30.6%), M45 (29.3%), M172 (26.6%) and M173 (22.6%). The Y-chromosome haplogroups of Antalya population were defined by these 18 Y-SNP polymorphic loci and the frequencies and the distribution of haplogroups were determined. J2*(xJ2F2) (26.6%), K*(xN3,O,P) (13.3%), E3b (9.3%), F*(xH,I,J,K) (8%), R1a1*(xR1a1b) (8%), R1b*(xR1b1, R1b6, R1b8) (8%), P*(xQ3a,R1) (8%) haplogroups were identified as the most abundant in Antalya population. These haplogroups are reported as widespread also in European and neighboring Near Eastern populations.

Discussion on Internet

• http://community.haplozone.net/index.php?topic=1474.0
• http://dienekes.blogspot.com/2009/06/y-chromosomes-of-turks-from-antalya.html

E-M35 results

Out of 75 people tested:

D 0 people
E(xE1,E3a,E3b) 1 person
E-M78 4 people (5.3%)
E-M224 0 people
E-M81 0 people
E-M123 2 people (2.7%)